ENPP3
外核苷酸焦磷酸酶/磷酸二酯酶家族成員3是一種由ENPP3基因編碼的酶。Hiroaki在2013年的實驗中對N2a細胞進行研究，純化了存在于GnT-IX中的一種內源性抑制因子，發現其與外核苷酸焦磷酸酶/磷酸二酯酶3 (ENPP3)相同，這一結果通過質譜分析以及培養細胞中ENPP3的敲除和過表達得到了證明。動力學分析顯示，ENPP3導致的GnT-IX抑制機制是ENPP3介導的核苷酸糖供體底物UDP-GlcNAc水解，從而生成UMP(一種強效競爭性GnT-IX抑制劑)。實際上，當對細胞內的ENPP3敲除，細胞內核苷酸糖水平顯著升高，并顯示出細胞總糖基化特征的變化。除了糖基轉移酶的伴侶或其他已知調節劑外，ENPP3介導的核苷酸糖水解將對糖基轉移酶活性產生也會產生廣泛和顯著的影響，并負責改變細胞總糖基化特征和調節細胞功能。
熱銷產品
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 at 2 μg/ml can bind Anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 3.313-4.724 ng/mL.
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3 at 2 μg/ml can bind anti-ENPP3 recombinant antibody (CSB-RA007681MA1HU), the EC50 is 2.151-2.492 ng/mL.
● ENPP3 Recombinant Monoclonal Antibody CSB-RA007681MA1HU
驗證數據
The Binding Activity of Macaca fascicularis ENPP3 with Anti-ENPP3 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ENPP3 (CSB-MP4278MOV) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 3.313-4.724 ng/mL.
The Binding Activity of Huamn ENPP3 with Anti- ENPP3 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ENPP3(CSB-MP007681HU) at 2 μg/mL can bind Anti-ENPP3 recombinant antibody, the EC50 is 2.151-2.492 ng/mL
Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T stable cells (red line) were stained with anti-ENPP3 recombinant antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
● HEK293T/Human ENPP3 Stable Cell Line CSB-SC007681HU
驗證數據
Untransfected HEK293T cells (green line) and transfected Human ENPP3 HEK293T Stable cells (red line) were stained with anti-ENPP3 antibody (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
ENPP3 Antibodies
ENPP3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA005288 | ENPP3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA575380 | ENPP3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA448237 | ENPP3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA007681MA1HU | ENPP3 Recombinant Monoclonal Antibody | Human, Macaca fascicularis | ELISA,FC |
ENPP3 Proteins
ENPP3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007681RA CSB-EP007681RA CSB-BP007681RA CSB-MP007681RA CSB-EP007681RA-B |
Recombinant Rat Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Enpp3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007681BO CSB-EP007681BO CSB-BP007681BO CSB-MP007681BO CSB-EP007681BO-B |
Recombinant Bovine Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007681HU CSB-EP007681HU CSB-BP007681HU CSB-EP007681HU-B |
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP007681HU | Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial (Active) | Mammalian cell |
| CSB-MP007681HUb0 | Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial (Active) | Mammalian cell |
ENPP3 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP719125PYX CSB-EP719125PYX CSB-BP719125PYX CSB-MP719125PYX CSB-EP719125PYX-B |
Recombinant Pongo abelii Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (ENPP3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP735351MO CSB-EP735351MO CSB-BP735351MO CSB-MP735351MO CSB-EP735351MO-B |
Recombinant Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Enpp3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENPP3 ELISA Kit
ENPP3 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL007681HU | Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 3(ENPP3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 0.039 ng/mL |
