ENG
ENG全稱為內皮聯蛋白（Endoglin），別名CD105。它是一種I型跨膜糖蛋白，主要表達于內皮細胞、成纖維細胞和血管平滑肌細胞等。內皮聯蛋白作為TGF-β家族的輔助受體，通過與TGF-β受體復合體相互作用，調節細胞的增殖、遷移和分化，從而在血管生成和穩態維持中發揮關鍵作用。內皮聯蛋白還參與炎癥反應和免疫應答的調節。
ENG基因突變可導致1型遺傳性出血性毛細血管擴張癥（HHT1），表現為血管發育不良和反復出血。在腫瘤中，內皮聯蛋白高表達與腫瘤血管生成和轉移密切相關，因此成為抗腫瘤治療的重要靶點。針對內皮聯蛋白的藥物研發正在推進，旨在通過抑制其功能來阻斷腫瘤血管生成。
熱銷產品
驗證數據
Western blot analysis of K562 3T3 lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200
ENG Antibodies
ENG for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA007667GA01HU | ENG Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA400072 | ENG Antibody | Human | WB, IHC, ELISA |
| CSB-PA007667LA01HU | ENG Antibody | Human | ELISA, IF |
| CSB-PA007667LC01HU | ENG Antibody, FITC conjugated | Human | |
| CSB-PA007667LD01HU | ENG Antibody, Biotin conjugated | Human | ELISA |
| CSB-MA294403 | ENG Monoclonal Antibody | Human | ELISA, IHC |
ENG Proteins
ENG Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007667HU1 CSB-EP007667HU1 CSB-BP007667HU1 CSB-MP007667HU1 CSB-EP007667HU1-B |
Recombinant Human Endoglin (ENG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007667HU | Recombinant Human Endoglin (ENG) | in vitro E.coli expression system |
ENG Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007667PI1 CSB-EP007667PI1 CSB-BP007667PI1 CSB-MP007667PI1 CSB-EP007667PI1-B |
Recombinant Pig Endoglin (ENG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007667PI | Recombinant Pig Endoglin (ENG) | in vitro E.coli expression system |
ENG Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP007667MO CSB-EP007667MO CSB-BP007667MO CSB-MP007667MO CSB-EP007667MO-B |
Recombinant Mouse Endoglin (Eng), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ENG ELISA Kit
ENG ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E10030h | Human Soluble Endoglin,sENG/sCD105 ELISA Kit | serum, plasma, tissue homogenates | 0.047 ng/mL |
ENG ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09921m | Mouse Soluble Endoglin,ENG/sCD105 ELISA Kit | serum, plasma, tissue homogenates | 1.56 ng/mL |
