DLL1
DLL1，全稱為Delta-like 1 protein，是一種跨膜糖蛋白，屬于DSL（Delta, Serrate, Lag-2）蛋白家族成員。它作為Notch信號轉導通路的配體之一，在中樞神經系統的形態發生、椎間關節的形成、內耳毛細胞的發育和形成以及動脈的形成中起重要作用。DLL1參與調節神經、胰腺和肌原祖細胞、T淋巴細胞和B淋巴細胞的穩態和分化。它在許多癌癥中過表達，與腫瘤的發生相關。DLL1的胞外區域可以從細胞表面脫落，胞內結構域可以被γ-分泌酶剪切，轉移到細胞核，進而調控基因轉錄。DLL1蛋白在免疫系統中也發揮著重要作用，它能夠抑制腫瘤細胞的增殖和促進細胞分化，從而抑制腫瘤的生長。目前，DLL1蛋白已被認為是治療某些癌癥的潛在靶點，相關藥物研發正在進行中。
熱銷產品
Human Delta-like protein 1(DLL1) ELISA kit (CSB-EL006947HU)
驗證數據
貨號：CSB-EL006947HU
規格：96T/48T
靈敏度：7.8 pg/ml
檢測范圍：31.25 pg/ml - 2000 pg/ml
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
DLL1 Antibodies
DLL1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA006947GA01HU | DLL1 Antibody | Human | ELISA,WB |
DLL1 Proteins
DLL1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP006947RA1 CSB-EP006947RA1 CSB-BP006947RA1 CSB-MP006947RA1 CSB-EP006947RA1-B |
Recombinant Rat Delta-like protein 1 (Dll1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006947RA | Recombinant Rat Delta-like protein 1 (Dll1) | in vitro E.coli expression system |
DLL1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP006947HU1 CSB-EP006947HU1 CSB-BP006947HU1 CSB-MP006947HU1 CSB-EP006947HU1-B |
Recombinant Human Delta-like protein 1 (DLL1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF006947HU | Recombinant Human Delta-like protein 1 (DLL1) | in vitro E.coli expression system |
DLL1 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP345705XBE CSB-EP345705XBE CSB-BP345705XBE CSB-MP345705XBE CSB-EP345705XBE-B |
Recombinant Xenopus laevis Homeobox protein DLL-1 (dll1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP736821MO CSB-EP736821MO CSB-BP736821MO CSB-MP736821MO CSB-EP736821MO-B |
Recombinant Mouse Delta-like protein 1 (Dll1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DLL1 ELISA Kit
DLL1 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL006947HU | Human Delta-like protein 1(DLL1) ELISA kit | serum, plasma, tissue homogenates. | 7.8 pg/ml |
