DAB2IP
Disabled homolog 2-interacting protein is a protein in humans that is encoded by DAB2IP gene. Functions as a scaffold protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Involved in several processes such as innate immune response, inflammation and cell growth inhibition, apoptosis, cell survival, angiogenesis, cell migration and maturation. Plays also a role in cell cycle checkpoint control; reduces G1 phase cyclin levels resulting in G0/G1 cell cycle arrest. Mediates signal transduction by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF), interferon (IFN) or lipopolysaccharide (LPS). Modulates the balance between phosphatidylinositol 3-kinase (PI3K)-AKT-mediated cell survival and apoptosis stimulated kinase (MAP3K5)-JNK signaling pathways; sequesters both AKT1 and MAP3K5 and counterbalances the activity of each kinase by modulating their phosphorylation status in response to proinflammatory stimuli.
DAB2IP Antibodies
DAB2IP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA108593 | DAB2IP Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA167820 | DAB2IP Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA730138OA01HU | DAB2IP Antibody | Human | ELISA, IF |
| CSB-PA730138OB01HU | DAB2IP Antibody, HRP conjugated | Human | ELISA |
DAB2IP Proteins
DAB2IP Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP661038MO CSB-EP661038MO CSB-BP661038MO CSB-MP661038MO CSB-EP661038MO-B |
Recombinant Mouse Disabled homolog 2-interacting protein (Dab2ip), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DAB2IP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP730138HU CSB-EP730138HU CSB-BP730138HU CSB-MP730138HU CSB-EP730138HU-B |
Recombinant Human Disabled homolog 2-interacting protein (DAB2IP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DAB2IP Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP761301RA CSB-EP761301RA CSB-BP761301RA CSB-MP761301RA CSB-EP761301RA-B |
Recombinant Rat Disabled homolog 2-interacting protein (Dab2ip), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
