CENPF
CENPF is a protein in humans that is encoded by CENPF gene. Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. Regulates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubule network though its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellular processes during development by regulating the activity of RB proteins during cell division and proliferation. May play a regulatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regulation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regulating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regulation of T-cell immunity against chlamydia.
CENPF Antibodies
CENPF for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA230952 | CENPF Antibody | Human | ELISA,IHC |
| CSB-PA646140 | CENPF Antibody | Human | ELISA,IHC |
CENPF Proteins
CENPF Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP005210HU CSB-EP005210HU CSB-MP005210HU CSB-EP005210HU-B |
Recombinant Human Centromere protein F (CENPF), partial | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP005210HU | Recombinant Human Centromere protein F (CENPF), partial | Baculovirus |
