CBL
E3 ubiquitin-protein ligase CBL is a protein in humans that is encoded by CBL gene. Adapter protein that functions as a negative regulator of many signaling pathways that are triggered by activation of cell surface receptors. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including KIT, FLT1, FGFR1, FGFR2, PDGFRA, PDGFRB, EGFR, CSF1R, EPHA8 and KDR and terminates signaling. Recognizes membrane-bound HCK, SRC and other kinases of the SRC family and mediates their ubiquitination and degradation. Participates in signal transduction in hematopoietic cells.
CBL Antibodies
CBL for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA205538 | Phospho-CBL (Tyr700) Antibody | Human | ELISA,WB,IHC,IF |
| CSB-PA932513 | CBL (Ab-700) Antibody | Human | ELISA,WB,IHC |
| CSB-PA574497 | Phospho-CBL (Tyr674) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA001340 | CBL Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA001352 | CBL Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA070118 | Phospho-CBL (Y674) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA070119 | Phospho-CBL (Y774) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA070120 | Phospho-CBL (Y700) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA787303 | CBL Antibody | Human,Mouse | ELISA,WB |
| CSB-PA988596 | CBL Antibody | Human,Mouse | ELISA,WB |
| CSB-PA004578LA01HU | CBL Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA004578LC01HU | CBL Antibody, FITC conjugated | Human |
CBL Proteins
CBL Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004578HU CSB-EP004578HU CSB-BP004578HU CSB-MP004578HU CSB-EP004578HU-B |
Recombinant Human E3 ubiquitin-protein ligase CBL (CBL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBL Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP004578MO CSB-EP004578MO CSB-BP004578MO CSB-MP004578MO CSB-EP004578MO-B |
Recombinant Mouse E3 ubiquitin-protein ligase CBL (Cbl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBL Proteins for Enterobacter aerogenes (Aerobacter aerogenes)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP600505EKN CSB-EP600505EKN CSB-BP600505EKN CSB-MP600505EKN CSB-EP600505EKN-B |
Recombinant Enterobacter aerogenes HTH-type transcriptional regulator cbl (cbl) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CBL Proteins for Escherichia coli (strain K12)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP675086ENV CSB-EP675086ENV CSB-BP675086ENV CSB-MP675086ENV CSB-EP675086ENV-B |
Recombinant Escherichia coli HTH-type transcriptional regulator cbl (cbl) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
