CARD16
Caspase recruitment domain-containing protein 16 is a protein in humans that is encoded by CARD16 gene. Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
CARD16 Antibodies
CARD16 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA682727LA01HU | CARD16 Antibody | Human | ELISA, IF |
| CSB-PA682727LB01HU | CARD16 Antibody, HRP conjugated | Human | ELISA |
CARD16 Proteins
CARD16 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP682727HU CSB-EP682727HU CSB-BP682727HU CSB-MP682727HU CSB-EP682727HU-B |
Recombinant Human Caspase recruitment domain-containing protein 16 (CARD16) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
