AMER1
Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development.
AMER1 Antibodies
AMER1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA918886 | AMER1 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA281738 | AMER1 Antibody | Human,Mouse | ELISA,IHC |
AMER1 Proteins
AMER1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP515254DIL CSB-EP515254DIL CSB-BP515254DIL CSB-MP515254DIL CSB-EP515254DIL-B |
Recombinant Danio rerio APC membrane recruitment protein 1 (fam123b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AMER1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP683359HU CSB-EP683359HU CSB-BP683359HU CSB-MP683359HU CSB-EP683359HU-B |
Recombinant Human APC membrane recruitment protein 1 (FAM123B), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AMER1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP745882MO CSB-EP745882MO CSB-BP745882MO CSB-MP745882MO CSB-EP745882MO-B |
Recombinant Mouse APC membrane recruitment protein 1 (Fam123b), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
