ACP5
ACP5，即抗酒石酸酸性磷酸酶5。別名包括TRACP、TRAP，它是一種由第19號染色體上的基因編碼的單一同工酶，是一種結構高度保守的含鐵糖蛋白。ACP5主要存在于巨噬細胞、破骨細胞、Gaucher細胞、紅細胞、血小板、脾臟毛狀細胞以及單核吞噬細胞中，尤其在肺泡巨噬細胞和破骨細胞中含量最豐富。ACP5參與活性氧的生成、正常骨骼發(fā)育、成骨細胞調(diào)節(jié)和巨噬細胞功能，影響一系列途徑，并反映骨骼的吸收和破骨細胞活性。研究表明，RANKL可以通過NFATc1和c-Fos增加ACP5的表達，從而加速破骨細胞的生成。ACP5在預防、監(jiān)測和治療各種腫瘤以及加速發(fā)展人類遺傳疾病的有前景的治療策略中起著至關重要的作用。
熱銷產(chǎn)品
Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) (CSB-YP001178HU)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ACP5 Antibodies
ACP5 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA001178GA01HU | ACP5 Antibody | Human,Mouse,Rat | ELISA,IHC |
ACP5 Proteins
ACP5 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001178MO CSB-EP001178MO CSB-BP001178MO CSB-MP001178MO CSB-EP001178MO-B |
Recombinant Mouse Tartrate-resistant acid phosphatase type 5 (Acp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP001178HU CSB-BP001178HU CSB-EP001178HU-B |
Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) | E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-YP001178HU | Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast |
ACP5 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001178PI CSB-EP001178PI CSB-BP001178PI CSB-MP001178PI CSB-EP001178PI-B |
Recombinant Pig Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001178RB CSB-EP001178RB CSB-BP001178RB CSB-MP001178RB CSB-EP001178RB-B |
Recombinant Rabbit Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP001178RA CSB-EP001178RA CSB-BP001178RA CSB-MP001178RA CSB-EP001178RA-B |
Recombinant Rat Tartrate-resistant acid phosphatase type 5 (Acp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 ELISA Kit
ACP5 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08490h | Human tartrate-resistant acid phosphatase 5b,TRACP-5b ELISA Kit | serum, plasma, tissue homogenates | 0.078 mIU/mL |
ACP5 ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08492m | Mouse tartrate-resistant acid phosphatase 5b(TRACP-5b) ELISA Kit | serum, plasma, tissue homogenates | 0.02 mIU/mL |
ACP5 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E15043Rb | Rabbit Tartrate-resistant acid phosphatase 5b (TRAP5b) ELISA Kit | serum, plasma, tissue homogenates | 19.5 μU/mL |
