SLC1A2
SLC1A2，即溶質(zhì)載體家族1成員2，別名EAAT2、GLT-1等。它是一種由SLC1A2基因編碼的跨膜蛋白，主要在大腦神經(jīng)元和膠質(zhì)細(xì)胞中表達(dá)。SLC1A2的作用機(jī)制涉及介導(dǎo)細(xì)胞外谷氨酸的轉(zhuǎn)運(yùn)，將其帶入細(xì)胞內(nèi)，對維持中樞神經(jīng)系統(tǒng)的谷氨酸穩(wěn)態(tài)至關(guān)重要。SLC1A2參與了神經(jīng)遞質(zhì)谷氨酸的再攝取過程，對調(diào)節(jié)神經(jīng)興奮性和抑制性平衡具有重要作用。SLC1A2的功能異常與多種神經(jīng)系統(tǒng)疾病有關(guān)，如癲癇、神經(jīng)退行性疾病、腦損傷等。
熱銷產(chǎn)品
SLC1A2 Recombinant Monoclonal Antibody (CSB-RA051685A0HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: EAAT2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62 kDa
Observed band size: 62 kDa
Overlay Peak curve showing MCF-7 cells surface stained with CSB-RA051685A0HU (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
SLC1A2 Antibodies
SLC1A2 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA109577 | SLC1A2 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA302626 | SLC1A2 Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA021433LA01HU | SLC1A2 Antibody | Human, Rat, Mouse | ELISA, WB, IHC, IF |
| CSB-PA021433LC01HU | SLC1A2 Antibody, FITC conjugated | Human | |
| CSB-PA021433LD01HU | SLC1A2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA051685A0HU | SLC1A2 Recombinant Monoclonal Antibody | Human | ELISA, WB, FC |
SLC1A2 Proteins
SLC1A2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021433RA CSB-EP021433RA CSB-BP021433RA CSB-MP021433RA CSB-EP021433RA-B |
Recombinant Rat Excitatory amino acid transporter 2 (Slc1a2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC1A2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021433HU CSB-EP021433HU CSB-BP021433HU CSB-MP021433HU CSB-EP021433HU-B |
Recombinant Human Excitatory amino acid transporter 2 (SLC1A2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC1A2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP021433MO | Recombinant Mouse Excitatory amino acid transporter 2 (Slc1a2), partial | Yeast |
| CSB-EP021433MO | Recombinant Mouse Excitatory amino acid transporter 2 (Slc1a2), partial | E.coli |
