NGF
NGF，即神經(jīng)生長因子，別名Nerve Growth Factor。它是一種在多種組織中廣泛存在，尤其在中樞和外周神經(jīng)系統(tǒng)中具有重要作用的蛋白質(zhì)。NGF由人體細(xì)胞自身的基因編碼，最初從小鼠腫瘤、蛇毒和雄性小鼠唾液腺中被分離和純化出來 。NGF的作用機(jī)制主要是通過與其高親和力受體TrkA結(jié)合，激活細(xì)胞內(nèi)的酪氨酸激酶活性，進(jìn)而觸發(fā)下游的PI3K-Akt和MAPK等信號通路，促進(jìn)神經(jīng)元的存活、分化和生長。此外，NGF還能與低親和力受體p75NTR結(jié)合，參與調(diào)節(jié)細(xì)胞凋亡等過程 。在生物學(xué)意義上，NGF對神經(jīng)系統(tǒng)的發(fā)育和成熟至關(guān)重要，特別是在促進(jìn)特定類型神經(jīng)細(xì)胞的存活和功能表達(dá)方面。NGF的活性還與免疫細(xì)胞的活性調(diào)節(jié)、腫瘤細(xì)胞的有絲分裂抑制以及創(chuàng)口愈合過程相關(guān)。在疾病治療方面，NGF被研究用于治療包括阿爾茨海默病、帕金森病、糖尿病相關(guān)神經(jīng)病變和急性神經(jīng)系統(tǒng)損傷等多種疾病 。
熱銷產(chǎn)品
Recombinant Human Beta-nerve growth factor (NGF) (CSB-EP015779HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
NGF Recombinant Monoclonal Antibody (CSB-RA015779MA1HU)
驗(yàn)證數(shù)據(jù)
Overlay Peak curve showing PC3 cells stained with CSB-RA015779MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was human IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
NGF Antibodies
NGF for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA16859B0Rb | Ngf Antibody, HRP conjugated | Rat | ELISA |
| CSB-PA16859A0Rb | Ngf Antibody | Rat | ELISA, IP |
NGF for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA015779GA01HU | NGF Antibody | Human | ELISA,IHC |
| CSB-PA003446 | NGF Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA006132 | NGF Antibody | Human | WB, ELISA |
| CSB-PA942456 | NGF Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA558560 | NGF Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA643662LA01HU | NGF Antibody | Human | ELISA, IHC |
| CSB-PA643662LB01HU | NGF Antibody, HRP conjugated | Human | ELISA |
| CSB-PA643662LC01HU | NGF Antibody, FITC conjugated | Human | |
| CSB-PA643662LD01HU | NGF Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA288635A0HU | NGF Recombinant Monoclonal Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-RA015779MA1HU | NGF Recombinant Monoclonal Antibody | Human | ELISA, FC |
NGF for Pig
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA643662LA01PI | NGF Antibody | Pig | ELISA |
| CSB-PA643662LB01PI | NGF Antibody, HRP conjugated | Pig | ELISA |
| CSB-PA643662LC01PI | NGF Antibody, FITC conjugated | Pig | |
| CSB-PA643662LD01PI | NGF Antibody, Biotin conjugated | Pig | ELISA |
NGF Proteins
NGF Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779BO CSB-EP015779BO CSB-BP015779BO CSB-MP015779BO CSB-EP015779BO-B |
Recombinant Bovine Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779GU CSB-EP015779GU CSB-BP015779GU CSB-MP015779GU CSB-EP015779GU-B |
Recombinant Guinea pig Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779RA | Recombinant Rat Beta-nerve growth factor (Ngf) | Yeast |
| CSB-EP015779RA1 | Recombinant Rat Beta-nerve growth factor (Ngf), partial | E.coli |
| CSB-EP015779RA CSB-BP015779RA CSB-MP015779RA CSB-EP015779RA-B |
Recombinant Rat Beta-nerve growth factor (Ngf) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779HU CSB-BP015779HU CSB-MP015779HU CSB-EP015779HU-B |
Recombinant Human Beta-nerve growth factor (NGF) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003771HU | Recombinant Human Beta-nerve growth factor (NGF) (Active) | E.coli |
| CSB-AP003951HU | Recombinant Human Beta-nerve growth factor (NGF), partial (Active) | Mammalian cell |
| CSB-EP015779HU | Recombinant Human Beta-nerve growth factor (NGF) | E.coli |
NGF Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779CH CSB-EP015779CH CSB-BP015779CH CSB-MP015779CH CSB-EP015779CH-B |
Recombinant Chicken Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779MO CSB-EP015779MO CSB-BP015779MO CSB-MP015779MO CSB-EP015779MO-B |
Recombinant Mouse Beta-nerve growth factor (Ngf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP004081MO | Recombinant Mouse Beta-nerve growth factor (Ngf), partial (Active) | E.coli |
| CSB-AP004101MO | Recombinant Mouse Beta-nerve growth factor (Ngf) (Active) | E.coli |
NGF Proteins for Praomys natalensis (African soft-furred rat) (Mastomys natalensis)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP015779PRP CSB-EP015779PRP CSB-BP015779PRP CSB-MP015779PRP CSB-EP015779PRP-B |
Recombinant Praomys natalensis Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP324224XBE CSB-EP324224XBE CSB-BP324224XBE CSB-MP324224XBE CSB-EP324224XBE-B |
Recombinant Xenopus laevis Nerve growth factor (ngf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Xiphophorus maculatus (Southern platyfish) (Platypoecilus maculatus)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP341491XAS CSB-EP341491XAS CSB-BP341491XAS CSB-MP341491XAS CSB-EP341491XAS-B |
Recombinant Xiphophorus maculatus Nerve growth factor (ngf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP643662PI CSB-BP643662PI CSB-MP643662PI CSB-EP643662PI-B |
Recombinant Pig Beta-nerve growth factor (NGF) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP643662PI | Recombinant Pig Beta-nerve growth factor (NGF) | E.coli |
NGF Proteins for Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP705448SWC CSB-EP705448SWC CSB-BP705448SWC CSB-MP705448SWC CSB-EP705448SWC-B |
Recombinant Saimiri boliviensis boliviensis Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP751089DIL CSB-EP751089DIL CSB-BP751089DIL CSB-MP751089DIL CSB-EP751089DIL-B |
Recombinant Danio rerio Nerve growth factor (ngf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Bothrops jararacussu (Jararacussu)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP852675BUX CSB-EP852675BUX CSB-BP852675BUX CSB-MP852675BUX CSB-EP852675BUX-B |
Recombinant Bothrops jararacussu Venom nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP868235GGZ CSB-EP868235GGZ CSB-BP868235GGZ CSB-MP868235GGZ CSB-EP868235GGZ-B |
Recombinant Gorilla gorilla gorilla Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Pongo pygmaeus (Bornean orangutan)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP873567EXP CSB-EP873567EXP CSB-BP873567EXP CSB-MP873567EXP CSB-EP873567EXP-B |
Recombinant Pongo pygmaeus Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF Proteins for Pan troglodytes (Chimpanzee)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP882018EQV CSB-EP882018EQV CSB-BP882018EQV CSB-MP882018EQV CSB-EP882018EQV-B |
Recombinant Pan troglodytes Beta-nerve growth factor (NGF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NGF ELISA Kit
NGF ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04683h | Human Nerve growth factor,NGF ELISA kit | serum, plasma, cell culture supernates, tissue homogenates, cell lysates. | 6.86 pg/ml. |
NGF ELISA Kit for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04684m | Mouse Nerve growth factor,NGF ELISA kit | serum, plasma, tissue homogenates. | 15.6 pg/ml |
NGF ELISA Kit for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04685r | Rat Nerve growth factor,NGF ELISA kit | serum, plasma, tissue homogenates | 0.195 pg/mL |
