IL24

IL24，即白細(xì)胞介素24，它是一種由T細(xì)胞、B細(xì)胞、巨噬細(xì)胞和樹突狀細(xì)胞等多種免疫細(xì)胞產(chǎn)生的細(xì)胞因子。IL24屬于IL-10細(xì)胞因子家族，通過與特異性受體復(fù)合體結(jié)合，如IL20RA/IL20RB或IL20RB/IL22RA1，激活下游的JAK-STAT信號通路，進(jìn)而調(diào)控免疫反應(yīng)和細(xì)胞增殖。其作用機(jī)制包括促進(jìn)腫瘤細(xì)胞凋亡、抑制腫瘤血管生成，以及增強(qiáng)對放化療的敏感性。在生物學(xué)意義上，IL24具有抗腫瘤活性，其表達(dá)水平與多種腫瘤的低惡性和轉(zhuǎn)移性相關(guān)，是腫瘤治療和免疫調(diào)節(jié)的潛在靶點(diǎn)。

熱銷產(chǎn)品

IL24 Antibody (CSB-PA613378LA01HU)

驗(yàn)證數(shù)據(jù)

IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IL24 Antibody

IL24 Protein

IL24 ELISA Kit

IL24 Antibodies

IL24 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA011640GA01HU	IL24 Antibody	Human,Mouse	ELISA,WB
CSB-PA005671	IL24 Antibody	Human	WB, ELISA
CSB-PA613378LA01HU	IL24 Antibody	Human	ELISA, IHC
CSB-PA613378LB01HU	IL24 Antibody, HRP conjugated	Human	ELISA
CSB-PA613378LC01HU	IL24 Antibody, FITC conjugated	Human
CSB-PA613378LD01HU	IL24 Antibody, Biotin conjugated	Human	ELISA

IL24 Proteins

IL24 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP613378HU CSB-EP613378HU CSB-BP613378HU CSB-MP613378HU CSB-EP613378HU-B	Recombinant Human Interleukin-24 (IL24)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL24 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP821683MO CSB-EP821683MO CSB-BP821683MO CSB-MP821683MO CSB-EP821683MO-B	Recombinant Mouse Interleukin-24 (Il24)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL24 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP881300RA CSB-EP881300RA CSB-BP881300RA CSB-MP881300RA CSB-EP881300RA-B	Recombinant Rat Interleukin-24 (Il24)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli