Recombinant Xenopus laevis E3 ubiquitin-protein ligase RING2-A (rnf2-a)

中文名稱(chēng)：

有爪蟾蜍rnf2-a重組蛋白
貨號(hào)：

CSB-YP717956XBE
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

有爪蟾蜍rnf2-a重組蛋白
貨號(hào)：

CSB-EP717956XBE
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

有爪蟾蜍rnf2-a重組蛋白
貨號(hào)：

CSB-EP717956XBE-B
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

有爪蟾蜍rnf2-a重組蛋白
貨號(hào)：

CSB-BP717956XBE
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

有爪蟾蜍rnf2-a重組蛋白
貨號(hào)：

CSB-MP717956XBE
說(shuō)明書(shū)：

MSDS Datasheet
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

rnf2-a
Uniprot No.：

Q66J69
別名：

rnf2-a; ring1b-a; E3 ubiquitin-protein ligase RING2-A; EC 2.3.2.27; RING finger protein 1B-A; RING1b-A; RING finger protein 2-A; RING-type E3 ubiquitin transferase RING2-A
種屬：

Xenopus laevis (African clawed frog)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-344
氨基酸序列

MATPVNAQCS SKTWELSLYE LHRTPQEAIM DGTEIAVSPR SLHSELMCPI CLDMLKNTMT TKECLHRFCS DCIVTALRSG NKECPTCRKK LVSKRSLRPD PNFDALISKI YPSRDEYEAH QDRVLAKLNR LHNQQALSSS IEEGLKMQAM HRAQRVRKHQ HESDNTTFSG GEDNCDSRSH VSNPSVHSNQ EAGPSRKRSR ASEDSGAEPD LSHEGGVRSP DPPGGGETGS EIELVFRAHP LLVEKDGYSQ TRYVKTTANA TVDHLSKYLA LRIALEEEVL RGEAEGVTLG EVSEKQYTIY ICTGVAGGQY TTLNGSLTLE LVNEKYWKVS KPLELYYAPT KEQK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.
亞細(xì)胞定位：

Nucleus. Cytoplasm. Chromosome.
數(shù)據(jù)庫(kù)鏈接：

KEGG: xla:447471

UniGene: Xl.6549