Recombinant Staphylococcus aureus Sensor protein srrB (srrB), partial

中文名稱：

金黃色釀膿葡萄球菌srrB重組蛋白
貨號：

CSB-YP642067FLF
規格：
來源：

Yeast
其他：

中文名稱：

金黃色釀膿葡萄球菌srrB重組蛋白
貨號：

CSB-EP642067FLF
規格：
來源：

E.coli
其他：

中文名稱：

金黃色釀膿葡萄球菌srrB重組蛋白
貨號：

CSB-EP642067FLF-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

金黃色釀膿葡萄球菌srrB重組蛋白
貨號：

CSB-BP642067FLF
規格：
來源：

Baculovirus
其他：

中文名稱：

金黃色釀膿葡萄球菌srrB重組蛋白
貨號：

CSB-MP642067FLF
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

srrB
Uniprot No.：

Q2FY80
別名：

srrB; SAOUHSC_01585; Sensor protein SrrB; EC 2.7.13.3; Staphylococcal respiratory response protein B
種屬：

Staphylococcus aureus (strain NCTC 8325)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation. Plays also an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate. Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to SrrA. In turn, SrrA binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
基因功能參考文獻：
1. The authors propose a model whereby SrrAB-dependent regulatory patterns facilitate the adaptation of cells to changes in dioxygen concentrations, and thereby aids in the prevention of H2O2 intoxication during respiratory growth upon dixoygen. PMID: 28099473
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
數據庫鏈接：

KEGG: sao:SAOUHSC_01585

STRING: 93061.SAOUHSC_01585