Recombinant Rat Ras-related protein Rap-1b (Rap1b)

中文名稱：

大鼠Rap1b重組蛋白
貨號：

CSB-YP717271RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Rap1b重組蛋白
貨號：

CSB-EP717271RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Rap1b重組蛋白
貨號：

CSB-EP717271RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Rap1b重組蛋白
貨號：

CSB-BP717271RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Rap1b重組蛋白
貨號：

CSB-MP717271RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rap1b
Uniprot No.：

Q62636
別名：

Rap1b; Ras-related protein Rap-1b; GTP-binding protein smg p21B
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-181
氨基酸序列

MREYKLVVLG SGGVGKSALT VQFVQGIFVE KYDPTIEDSY RKQVEVDAQQ CMLEILDTAG TEQFTAMRDL YMKNGQGFAL VYSITAQSTF NDLQDLREQI LRVKDTDDVP MILVGNKCDL EDERVVGKEQ GQNLARQWSN CAFLESSAKS KINVNEIFYD LVRQINRKTP VPGKARKKSS C
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
基因功能參考文獻：
1. Data indicate that mutations at different sites affect the ability of rap GTP-Binding Protein Rap1 to activate appropriately. PMID: 25935485
2. These data establish rap1b as a novel gene rapidly induced by GnRH and a candidate to modulate gonadotropin secretion in rat gonadotropes. PMID: 22127306
3. On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b. PMID: 11959997
4. cAMP inhibits Akt via Rap1b PMID: 12089143
亞細胞定位：

Cell membrane. Cytoplasm, cytosol. Cell junction.
蛋白家族：

Small GTPase superfamily, Ras family
數據庫鏈接：

KEGG: rno:171337

STRING: 10116.ENSRNOP00000009511

UniGene: Rn.95071