Recombinant Mouse Ran-binding protein 10 (Ranbp10)

中文名稱：

小鼠Ranbp10重組蛋白
貨號：

CSB-YP757810MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Ranbp10重組蛋白
貨號：

CSB-EP757810MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Ranbp10重組蛋白
貨號：

CSB-EP757810MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ranbp10重組蛋白
貨號：

CSB-BP757810MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ranbp10重組蛋白
貨號：

CSB-MP757810MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ranbp10
Uniprot No.：

Q6VN19
別名：

Ranbp10; Kiaa1464; Ran-binding protein 10; RanBP10
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

2-620
氨基酸序列

AAATADPGA GNPQAGDSSG GDSGGGLPSP GEQELSRRLQ RLYPAVNQHE TPLPRSWSPK DKYNYIGLSQ GNLRVHYKGH GKNHKDAASV RATHPIPAAC GIYYFEVKIV SKGRDGYMGI GLSAQGVNMN RLPGWDKHSY GYHGDDGHSF CSSGTGQPYG PTFTTGDVIG CCVNLINGTC FYTKNGHSLG IAFTDLPANL YPTVGLQTPG EIVDANFGQQ PFLFDIEDYM REWRAKVQGT VHGFPISARL GEWQAVLQNM VSSYLVHHGY CSTATAFARM TETPIQEEQA SIKNRQKIQK LVLEGRVGEA IETTQRFYPG LLEHNPNLLF MLKCRQFVEM VNGTDSEVRS LSSRSPKSQD SYPGSPSLSP RHGPSSSHIH NTGADSPSCS NGVASTKNKQ NHSKYPAPSS SSSSSSSSSS SSPSSVNYSE SNSTDSTKSQ PHSSTSNQET SDSEMEMEAE HYPNGVLESV STRIVNGAYK HDDLQTDESS MDDGHPRRQL CGGNQAATER IILFGRELQA LSEQLGREYG KNLAHTEMLQ DAFSLLAYSD PWSCPVGHQL DPIQREPVCA ALNSAILESQ NLPKQPPLML ALGQASECLR LMARAGLGSC SFARVDDYLH
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function.
基因功能參考文獻：
1. RanBP10 inhibits premature microtubule polymerization of beta1-tubulin and plays a pivotal role in thrombus stabilization. PMID: 22936655
2. Data suggest that RanBP10 plays an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function. PMID: 19801445
亞細胞定位：

Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associates with cytoplasmic microtubules in mature megakaryocytes and platelets.
蛋白家族：

RANBP9/10 family
組織特異性：

Expressed at highest levels in spleen and liver. Expressed in megakaryocytes and platelets (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: mmu:74334

STRING: 10090.ENSMUSP00000040045

UniGene: Mm.4206