Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog (Cwc22), partial

中文名稱：

Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog(Cwc22) ,partial
貨號：

CSB-YP803998MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog(Cwc22) ,partial
貨號：

CSB-EP803998MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog(Cwc22) ,partial
貨號：

CSB-EP803998MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog(Cwc22) ,partial
貨號：

CSB-BP803998MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Pre-mRNA-splicing factor CWC22 homolog(Cwc22) ,partial
貨號：

CSB-MP803998MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cwc22
Uniprot No.：

Q8C5N3
別名：

Cwc22; NcmPre-mRNA-splicing factor CWC22 homolog; Nucampholin homolog
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.
基因功能參考文獻：
1. These findings identify subtle but significant alterations in spliceosome structure and function, including dysregulated Cajal bodies and CWC22 overexpression, in diabetic sensory neurons that offer new ideas regarding diabetic sensory neurodegeneration in polyneuropathy. PMID: 28250049
2. Authors have reconstructed the origin and history of a 127-kbp segmental duplication, R2d, in the house mouse (Mus musculus). R2d contains a single protein-coding gene, Cwc22 De novo assembly of both the ancestral (R2d1) and the derived (R2d2) copies reveals that they have been subject to nonallelic gene conversion events spanning tens of kilobases. PMID: 27371833
亞細胞定位：

Nucleus. Nucleus speckle.
蛋白家族：

CWC22 family
數據庫鏈接：

KEGG: mmu:80744

STRING: 10090.ENSMUSP00000064947

UniGene: Mm.288151