Recombinant Mouse Opticin (Optc)

中文名稱：

小鼠Optc重組蛋白
貨號：

CSB-YP016362MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Optc重組蛋白
貨號：

CSB-EP016362MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Optc重組蛋白
貨號：

CSB-EP016362MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Optc重組蛋白
貨號：

CSB-BP016362MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Optc重組蛋白
貨號：

CSB-MP016362MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Optc
Uniprot No.：

Q920A0
別名：

Optc; Opt; Opticin; Oculoglycan
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

20-328
氨基酸序列

A SLLGEREREE QSPEEGDTYA SLYVGNHTLS IEDYNEVIDL SNYEELADYG DQIPEAKISN LTLPTRTSPT STVAQKTLSP NLTMAVPTTT GLLNSQSSHG LPTCLVCVCL GSSVYCDDAD LENIPPLPQM TTYLYARFNH ISHIQAGDFK GLTKLRRIDL SGNSISSIHN DALRLLPALQ DLILPENQLA ALPVLPSGIE FLDVRLNRLQ SSGIQPEAFV ALKKLQFLYL ANNMLDSIPG PLPLSLRSLH LQNNMIETME SDTFCDTGEH RHERRQLEDI RLDGNPINLS LFPEAYFCLP RLPVGHFT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Inhibits angiogenesis in the vitreous humor of the eye, and therefore represses neovascularization. Binds collagen fibrils. May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily.
基因功能參考文獻：
1. opticin binds to collagen and thereby competitively inhibits endothelial cell interactions with collagen via alpha(1)beta(1) and alpha(2)beta(1) integrins, thereby preventing the strong adhesion that is required for proangiogenic signaling via these integrins. PMID: 22669977
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Small leucine-rich proteoglycan (SLRP) family, SLRP class III subfamily
組織特異性：

Expressed in cartilage (at protein level). Expressed in the vitreous collagen, inner limiting membrane, lens capsule, trabecular meshwork, anterior surface of the iris, the area adjacent to the nonpigmented ciliary epithelium, and weakly expressed in the
數據庫鏈接：

KEGG: mmu:269120

STRING: 10090.ENSMUSP00000120568

UniGene: Mm.59985