Recombinant Mouse CD99 antigen (Cd99), partial

中文名稱(chēng)：

Recombinant Mouse CD99 antigen(Cd99),partial
貨號(hào)：

CSB-YP855325MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

Recombinant Mouse CD99 antigen(Cd99),partial
貨號(hào)：

CSB-EP855325MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

Recombinant Mouse CD99 antigen(Cd99),partial
貨號(hào)：

CSB-EP855325MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

Recombinant Mouse CD99 antigen(Cd99),partial
貨號(hào)：

CSB-BP855325MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

Recombinant Mouse CD99 antigen(Cd99),partial
貨號(hào)：

CSB-MP855325MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cd99
Uniprot No.：

Q8VCN6
別名：

Cd99; PilrlCD99 antigen; Paired immunoglobin-like type 2 receptor-ligand; PILR-L; CD antigen CD99
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Involved in T-cell adhesion processes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1.
基因功能參考文獻(xiàn)：
1. endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1. PMID: 28223280
2. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration. PMID: 26101266
3. role in membrane trafficking of CD99L2 and in controlling transendothelial migration of leukocytes PMID: 24133166
4. CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells. PMID: 22350746
5. CD99L2 and CD99 are involved in transendothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum PMID: 17344467
6. These findings indicate that sialylated O-linked sugar structures on CD99 play an important role in the recognition of PILR. PMID: 18209065
7. Vaccination against CD99 inhibits atherogenesis in low-density lipoprotein receptor-deficient mice. PMID: 18250143
8. Mouse CD99 is expressed on mouse leukocytes as well as enriched at the endothelial cell borders. PMID: 18923973
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亞細(xì)胞定位：

Membrane; Single-pass type I membrane protein.
蛋白家族：

CD99 family
組織特異性：

Widely expressed with high levels in lung, spleen, thymus, liver and spinal chord. Expressed on leukocytes and endothelial cell contacts. Detected in a wide range of T-cells, including CD4-/CD8- and CD4+/CD8+ thymocytes. Expression is much lower in periph
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:673094

UniGene: Mm.423040