Recombinant Human WASH complex subunit 7 (KIAA1033), partial

中文名稱：

人WASHC4重組蛋白
貨號：

CSB-YP645740HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人WASHC4重組蛋白
貨號：

CSB-EP645740HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人WASHC4重組蛋白
貨號：

CSB-EP645740HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人WASHC4重組蛋白
貨號：

CSB-BP645740HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人WASHC4重組蛋白
貨號：

CSB-MP645740HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

WASHC4
Uniprot No.：

Q2M389
別名：

Kiaa1033; WAHS4_HUMAN; WAHS7_HUMAN; WASH complex subunit 7; WASHC4
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
基因功能參考文獻(xiàn)：
1. Ten KIAA1033 SNPs were also significantly associated with AD in a group of African Americans. PMID: 22673115
2. SWIP is a novel gene for non-syndromic autosomal recessive intellectual disability PMID: 21498477
相關(guān)疾病：

Mental retardation, autosomal recessive 43 (MRT43)
亞細(xì)胞定位：

Early endosome.
蛋白家族：

SWIP family
數(shù)據(jù)庫鏈接：

HGNC: 29174

OMIM: 615748

KEGG: hsa:23325

STRING: 9606.ENSP00000328062

UniGene: Hs.12144