Recombinant Human Ragulator complex protein LAMTOR4 (LAMTOR4)

中文名稱：

人LAMTOR4重組蛋白
貨號(hào)：

CSB-YP613151HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人LAMTOR4重組蛋白
貨號(hào)：

CSB-EP613151HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

人LAMTOR4重組蛋白
貨號(hào)：

CSB-EP613151HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LAMTOR4重組蛋白
貨號(hào)：

CSB-BP613151HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人LAMTOR4重組蛋白
貨號(hào)：

CSB-MP613151HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

LAMTOR4
Uniprot No.：

Q0VGL1
別名：

AV006840; C7orf59; CG059_HUMAN; Chromosome 7 open reading frame 59 ; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; Ragulator complex protein LAMTOR4; UPF0539 protein C7orf59
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-99
氨基酸序列

MTSALTQGLE RIPDQLGYLV LSEGAVLASS GDLENDEQAA SAISELVSTA CGFRLHRGMN VPFKRLSVVF GEHTLLVTVS GQRVFVVKRQ NRGREPIDV
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
基因功能參考文獻(xiàn)：
1. Study identified HBXIP and C7orf59 as two additional Ragulator components that are required for mTORC1 activation by amino acids. PMID: 22980980
亞細(xì)胞定位：

Lysosome.
蛋白家族：

LAMTOR4 family
數(shù)據(jù)庫(kù)鏈接：

HGNC: 33772

KEGG: hsa:389541

STRING: 9606.ENSP00000343118

UniGene: Hs.406520