Recombinant Human Protocadherin-20 (PCDH20), partial

中文名稱：

人PCDH20重組蛋白
貨號：

CSB-YP822719HU
規格：
來源：

Yeast
其他：

中文名稱：

人PCDH20重組蛋白
貨號：

CSB-EP822719HU
規格：
來源：

E.coli
其他：

中文名稱：

人PCDH20重組蛋白
貨號：

CSB-EP822719HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PCDH20重組蛋白
貨號：

CSB-BP822719HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人PCDH20重組蛋白
貨號：

CSB-MP822719HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PCDH20
Uniprot No.：

Q8N6Y1
別名：

FLJ22218; PCD20_HUMAN; PCDH 13; PCDH 20; PCDH13; PCDH20; Protocadherin 13; Protocadherin 20; Protocadherin-13; Protocadherin-20; Protocadherin13; Protocadherin20
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Potential calcium-dependent cell-adhesion protein.
基因功能參考文獻：
1. low expression of PCDH20 was found to be associated with poor OS in HCC patients; hence, this protein represents a promising potential prognostic biomarker PMID: 27935871
2. Study shows that PCDH20 expression is downregulated in nasopharyngeal carcinoma cells (NPC) and identified it as a functional tumor suppressor and an important antagonist of Wnt/beta-catenin signaling and EMT, with frequent epigenetic inactivation in NPC. PMID: 25736877
3. In conclusion, these data here strongly suggested that PCDH20 may act as a candidate tumour suppressor in hepatocellular carcinoma. PMID: 24910204
亞細胞定位：

Cell membrane; Single-pass type I membrane protein.
數據庫鏈接：

HGNC: 14257

OMIM: 614449

KEGG: hsa:64881

STRING: 9606.ENSP00000386653

UniGene: Hs.391781