Recombinant Human Chemokine-like protein TAFA-5 (TAFA5)

中文名稱：

人TAFA5重組蛋白
貨號：

CSB-YP773595HU
規格：
來源：

Yeast
其他：

中文名稱：

人TAFA5重組蛋白
貨號：

CSB-EP773595HU
規格：
來源：

E.coli
其他：

中文名稱：

人TAFA5重組蛋白
貨號：

CSB-EP773595HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TAFA5重組蛋白
貨號：

CSB-BP773595HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人TAFA5重組蛋白
貨號：

CSB-MP773595HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FAM19A5
Uniprot No.：

Q7Z5A7
別名：

TAFA5; FAM19A5; UNQ5208/PRO34524; Chemokine-like protein TAFA-5
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

44-132aa
氨基酸序列

TCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVDARIIKTKQWCDMLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTVS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling. Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries.
亞細胞定位：

Secreted.
蛋白家族：

FAM19/TAFA family
組織特異性：

Expressed in the subcutaneous and perirenal adipose tissue (at protein level). Highly expressed in adipose tissue with moderate expression in the brain and ovary. Isoform 2: Brain-specific.
數據庫鏈接：

HGNC: 21592

OMIM: 617499

KEGG: hsa:25817

STRING: 9606.ENSP00000383933

UniGene: Hs.436854