Recombinant Human Methyl-CpG-binding domain protein 6 (MBD6), partial

中文名稱：

人MBD6重組蛋白
貨號：

CSB-YP846605HU
規格：
來源：

Yeast
其他：

中文名稱：

人MBD6重組蛋白
貨號：

CSB-EP846605HU
規格：
來源：

E.coli
其他：

中文名稱：

人MBD6重組蛋白
貨號：

CSB-EP846605HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MBD6重組蛋白
貨號：

CSB-BP846605HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人MBD6重組蛋白
貨號：

CSB-MP846605HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MBD6
Uniprot No.：

Q96DN6
別名：

MBD6; MBD6_HUMAN; Methyl-CpG-binding domain protein 6; Methyl-CpG-binding protein MBD6
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to heterochromatin. Does not interact with either methylated or unmethylated DNA (in vitro).
基因功能參考文獻：
1. Our findings imply that reduced stability and enhanced dynamics of MBD1 or MBD6 is the origin of ATP7B dysfunction in Wilson disease patients with the G85V or G591D mutation. PMID: 27744583
2. Frameshift mutations of MBD6 gene is associated with stomach and colorectal cancers. PMID: 25638327
3. This study demonstrates examples of autistic patients carrying alterations in MBD6. PMID: 23055267
4. MBD6 is regulated by Ago2 via an interaction with Oct4, which alters self-renewal and gene expression in human adipose tissue-derived stem cells. PMID: 23052207
亞細胞定位：

Nucleus. Chromosome. Note=Associated with pericentric heterochromatin in about 25% of the cells.
數據庫鏈接：

HGNC: 20445

KEGG: hsa:114785

STRING: 9606.ENSP00000347896

UniGene: Hs.524523