Recombinant Human Brain-specific angiogenesis inhibitor 2 (BAI2), partial

中文名稱：

Recombinant Human Brain-specific angiogenesis inhibitor 2(BAI2) ,partial
貨號：

CSB-YP523985HU
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Brain-specific angiogenesis inhibitor 2(BAI2) ,partial
貨號：

CSB-EP523985HU
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Brain-specific angiogenesis inhibitor 2(BAI2) ,partial
貨號：

CSB-EP523985HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Brain-specific angiogenesis inhibitor 2(BAI2) ,partial
貨號：

CSB-BP523985HU
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Brain-specific angiogenesis inhibitor 2(BAI2) ,partial
貨號：

CSB-MP523985HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ADGRB2
Uniprot No.：

O60241
別名：

ADGRB2; BAI2Adhesion G protein-coupled receptor B2; Brain-specific angiogenesis inhibitor 2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
基因功能參考文獻：
1. These studies provide new insights into the signaling capabilities of the adhesion GPCR BAI2/ADGRB2 and shed light on how an apparent gain-of-function mutation to the receptor's C-terminus may lead to human disease. PMID: 28891236
2. This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
3. BAI2 is a functional GPCR regulated by proteolytic processing and activates the NFAT pathway PMID: 20367554
4. involvement of BAI2 in the ischemia-induced brain angiogenesis PMID: 12218411
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
組織特異性：

Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
數據庫鏈接：

HGNC: 944

OMIM: 602683

KEGG: hsa:576

STRING: 9606.ENSP00000362762

UniGene: Hs.524138