PEF1 Recombinant Monoclonal Antibody
-
中文名稱：PEF1 Recombinant Monoclonal Antibody
-
貨號(hào)：CSB-RA179031A0HU
-
規(guī)格：￥1320
-
圖片：
-
Flow cytometric analysis of PEF1 expression in HeLa cells using PEF1 antibody. Green, isotype control; red, PEF1. -
Western blotting analysis using PEF1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with PEF1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
-
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：PEF1
-
別名：PEF1; Penta-EF-Hand Domain Containing 1; Peflin; PEF1A; PEF Protein With A Long N-Terminal Hydrophobic Domain; ABP32; Epididymis Secretory Sperm Binding Protein; Penta-EF Hand Domain-Containing Protein 1
-
反應(yīng)種屬：Human, Mouse, Rat
-
免疫原：Recombinant Human PEF1 protein
-
免疫原種屬：Homo sapiens (Human)
-
標(biāo)記方式：Non-conjugated
-
克隆類型：Monoclonal
-
抗體亞型：Rabbit IgG
-
純化方式：Affinity-chromatography
-
克隆號(hào)：10E11
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA, WB, FC
-
推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 -
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Together with PDCD6, acts as calcium-dependent adapter for the BCR(KLHL12) complex, a complex involved in endoplasmic reticulum (ER)-Golgi transport by regulating the size of COPII coats. In response to cytosolic calcium increase, the heterodimer formed with PDCD6 interacts with, and bridges together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export, which is required for neural crest specification. Its role in the heterodimer formed with PDCD6 is however unclear: some evidence shows that PEF1 and PDCD6 work together and promote association between PDCD6 and SEC31 in presence of calcium. Other reports show that PEF1 dissociates from PDCD6 in presence of calcium, and may act as a negative regulator of PDCD6. Also acts as a negative regulator of ER-Golgi transport; possibly by inhibiting interaction between PDCD6 and SEC31.
-
基因功能參考文獻(xiàn)：
- This work identifies for the first time a clear steady state role for a PEF protein in ER-to-Golgi transport-peflin is a negative regulator of transport. PMID: 27276012
- peflin is stabilized by dimerization through its fifth EF-hand region PMID: 11883899
-
亞細(xì)胞定位：Cytoplasm. Endoplasmic reticulum. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein.
-
數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
