TMEM2 Antibody

中文名稱：

TMEM2兔多克隆抗體
貨號：

CSB-PA23279A0Rb
規格：

￥440
圖片：
IHC image of CSB-PA23279A0Rb diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of A549 cells with CSB-PA23279A0Rb at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TMEM2 Polyclonal antibody
Uniprot No.：

Q9UHN6
基因名：

TMEM2
別名：

KIAA1412 antibody; TMEM 2 antibody; tmem2 antibody; TMEM2_HUMAN antibody; Transmembrane protein 2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Cell surface hyaluronidase protein (734-866AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TMEM2 Antibody (CSB-PA23279A0Rb)，的標記方式是Non-conjugated。對于TMEM2 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA23279B0Rb	TMEM2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA23279C0Rb	TMEM2 Antibody, FITC conjugated
Biotin	CSB-PA23279D0Rb	TMEM2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Unlike its mouse ortholog has no catalytic hyaluronic acid-degrading activity, but acts as a regulator of hyaluronan (HA) metabolism through regulation of expression of CEMIP and HAS2, two enzymes involved in HA depolymerization and HA synthesis, respectively.
基因功能參考文獻：
1. TMEM2 inhibits Hepatitis b virus infection in HepG2 and HepG2.2.15 by activating the JAK-STAT signaling pathway. PMID: 27253403
2. our findings lead us to propose that TMEM2 may not only mediate the pathologic effects of SOX4 on cancer progression but also potentially its contributions to embryonic development PMID: 27328729
3. Results showed that missense mutations in transmembrane protein 2 p.Ser1254Asn, interferon alpha 2 p.Ala120Thr, its regulator NLR family member X1 p.Arg707Cys, and complement component 2 p.Glu318Asp were associated with chronic hepatitis B. PMID: 22610944
亞細胞定位：

Cell membrane; Single-pass type II membrane protein.
蛋白家族：

TMEM2 family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 11869

OMIM: 605835

KEGG: hsa:23670

STRING: 9606.ENSP00000366243

UniGene: Hs.494146

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