TALDO1 Antibody

中文名稱：

TALDO1兔多克隆抗體
貨號：

CSB-PA04275A0Rb
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA04275A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA04275A0Rb at dilution of 1:100

Western blot
All lanes: TALDO1 antibody at 0.1µg/ml
Lane 1: Human placenta tissue
Lane 2: Hela whole cell lysate
Lane 3: Jurkat whole cell lysate
Lane 4: A375 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 38 kDa
Observed band size: 38 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TALDO1 Polyclonal antibody
Uniprot No.：

P37837
基因名：

TALDO1
別名：

Dihydroxyacetone transferase antibody; EC 2.2.1.2 antibody; EPS8L2 antibody; Glycerone transferase antibody; TAL antibody; TAL H antibody; TALDO antibody; TALDO_HUMAN antibody; TALDO1 antibody; TALDOR antibody; TALH antibody; Transaldolase 1 antibody; Transaldolase antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Transaldolase protein (9-337AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TALDO1 Antibody (CSB-PA04275A0Rb)，的標記方式是Non-conjugated。對于TALDO1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA04275B0Rb	TALDO1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA04275C0Rb	TALDO1 Antibody, FITC conjugated
Biotin	CSB-PA04275D0Rb	TALDO1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
基因功能參考文獻：
1. These results demonstrate that the nucleocytoplasmic distribution of TALDO1, modulated via alternative translational initiation and dimer formation, plays an important role in a wide range of metabolic networks PMID: 27703206
2. The above findings support the premise that biallelic mutations in TALDO1 are responsible for transaldolase deficiency and confirm the broad phenotypic variability of this condition, even with the same genotype. PMID: 25388407
3. This study expands the clinical definition of transaldolase deficiency, and adds to its allelic heterogeneity. PMID: 23315216
4. Data suggest that exchange reactions during gluconeogenesis catalyzed by transaldolase and triose-phosphate isomerase do not differ between subjects with type 2 diabetes and control subjects under fasting or hyperglycemic conditions. PMID: 23736541
5. renal phenotype of patients with transaldolase deficiency PMID: 22510381
6. these data provide strong experimental evidence that transaldolase exchange occurs in humans, resulting in an overestimate of gluconeogenesis PMID: 21062960
7. Data show that erythronic acid was identified as a major abnormal metabolite in all patients and in knock-out TALDO mice implicating an as yet unknown biochemical pathway in this disease. PMID: 20600873
8. granzyme B-cleaved transaldolase-specific T cell-mediated cytotoxicity may contribute to the progressive destruction of oligodendrocytes in patients with multiple sclerosis PMID: 20194725
9. transaldolase is regulated by ZNF143 in a tissue-specific manner PMID: 14702349
10. TALase undergoes anterograde trafficking in neutrophils from nonpregnant individuals, whereas retrograde trafficking is found during pregnancy PMID: 16092052
11. Mutation in the TALDO1 gene was found in patients with hydrops fetalis and neonatal multi-organ disease. PMID: 17095351
12. A patch of functionally important amino acid residues extends from serine-171 toward the catalytic site and is proposed as a novel ligand shuttling path connecting these specific sites to the enzyme's active site. PMID: 17503352
13. Transaldolase-deficient patients had significantly increased urinary heptoses, revealing novel urinary biomarkers for identification of the deficiency. PMID: 17603756
14. A new case of TALDO deficiency resulted in cirrhosis, rickets and deafness. PMID: 18331807
15. The present study identified the TAL deficiency as a modulator of mitochondrial homoeostasis, Ca(2+) fluxing and apoptosis. PMID: 18498245
16. analysis of enzymes TalB and Taldo1 in human and E. coli PMID: 18687684
17. genetic polymorphisms in Transaldolase 1 are associated with squamous cell carcinoma of the head and neck . PMID: 18805652
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相關疾病：

Transaldolase deficiency (TALDOD)
亞細胞定位：

Cytoplasm.
蛋白家族：

Transaldolase family, Type 1 subfamily
數據庫鏈接：

HGNC: 11559

OMIM: 602063

KEGG: hsa:6888

STRING: 9606.ENSP00000321259

UniGene: Hs.438678

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