Ctsk Antibody

^{Rare Species}

中文名稱：

Ctsk兔多克隆抗體
貨號：

CSB-PA006192LA01RA
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA006192LA01RA at dilution of 1:20
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Rattus norvegicus (Rat) Ctsk Polyclonal antibody
Uniprot No.：

O35186
基因名：

Ctsk
別名：

Ctsk antibody; Cathepsin K antibody; EC 3.4.22.38 antibody
宿主：

Rabbit
反應種屬：

Rat
免疫原：

Recombinant Rat Cathepsin K protein (115-329AA)
免疫原種屬：

Rattus norvegicus (Rat)

標記方式：

Non-conjugated

本頁面中的產(chǎn)品，Ctsk Antibody (CSB-PA006192LA01RA)，的標記方式是Non-conjugated。對于Ctsk Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產(chǎn)品名稱	應用
HRP	CSB-PA006192LB01RA	Ctsk Antibody, HRP conjugated	ELISA
FITC	CSB-PA006192LC01RA	Ctsk Antibody, FITC conjugated
Biotin	CSB-PA006192LD01RA	Ctsk Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:10-1:100

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

功能：

Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
基因功能參考文獻：
1. the present study identified icariin as a novel therapeutic agent in DXM-induced cartilage injury in rats, and revealed that the activation of miR-206 targeting of cathepsin K may be responsible for the chondroprotective efficacy of icariin PMID: 29207029
2. cathepsin K, in both its secreted and lysosomal forms, may play a role in the degradation of Sertoli cell residual bodies PMID: 14585819
3. In conclusion, according to its ability to modulate hypotensive effects of kinins, we propose that cathepsin K is a kininase of biological relevance. PMID: 17181996
4. Comparison of the S2 site between rat and human cathepsin K sequences indicated that two S2 residues at Ser134 and Val160 in rat are varied to Ala and Leu, respectively, in the human enzyme. PMID: 18664521
5. The expression pattern of Ctsk in osteoclasts in physiological root resorption in the rat molar was determined. PMID: 18974601
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亞細胞定位：

Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side.
蛋白家族：

Peptidase C1 family
數(shù)據(jù)庫鏈接：

KEGG: rno:29175

STRING: 10116.ENSRNOP00000028730

UniGene: Rn.5598

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