1. Loss of bikunin expression is associated with Embryos failing to Initiate Midgut Rotation. PMID: 30174180
2. In this review, the use of genetically targeted mice selectively lacking UTI provides evidence of a therapeutic option for experimental endotoxin-related inflammatory disorders such as acute lung injury and acute liver injury. PMID: 20367192
3. expression of the AMBP gene transcript and its two protein products, alpha(1)-microglobulin and bikunin, in embryogenesis PMID: 12204273
4. UTI inhibited LPS-induced production of TNF-alpha by inhibiting activation of the extracellular signal-regulated protein kinases 1/2-Egr-1 pathway in monocytes, which might at least partly contribute to reduction of hypotension PMID: 15539418
5. UTI protects against systemic inflammatory response and subsequent organ injury induced by bacterial endotoxin. PMID: 15576631
6. results indicate that endogenous UTI is protective against acute lung injury induced by bacterial endotoxin, at least partly, via the antioxidative properties PMID: 16273282
7. increased sensitivity of Bik-/- mice to lung metastasis in vivo is due to a lack of circulating proteins of the inter-alpha inhibitor family, especially bikunin PMID: 16331631
8. UTI reduces NF-kappaB activation and downregulates the expression of its related mediators, followed by the inhibition of neutrophil aggregation and infiltration in hepatic ischemia reperfusion injury PMID: 19208516
9. Report impaired liver regeneration with humoral and genetic disturbances in urinary trypsin inhibitor-deficient mice. PMID: 19302180
10. UTI protects against severe liver injury and subsequent coagulatory disturbance which was mediated, at least partly, through the suppression of TNF-alpha production along with its antiprotease activity. PMID: 19398962

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KEGG: mmu:11699

STRING: 10090.ENSMUSP00000030041

UniGene: Mm.2197