Monkey Interleukin-8,IL-8 ELISA Kit

說明書下載

產品詳情

產品描述：

猴子白介素8(IL-8/CXCL8)酶聯免疫試劑盒（CSB-E08051Mo）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織培養上清液、組織勻漿樣本中的CXCL8含量。CXCL8 作為靶點備受關注。它是趨化因子，在免疫調節、炎癥反應等生理病理過程中起重要作用。研究發現其能趨化中性粒細胞等免疫細胞遷移和活化。深入探究其與疾病發生發展的關聯及信號傳導機制，可為相關疾病治療提供新思路。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，在基礎研究領域，該產品可應用于靈長類動物模型中的感染性疾病機制探索、炎癥相關信號通路研究，以及抗炎藥物或免疫調節劑的體外篩選實驗。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

CXCL8 ELISA kit; IL8Interleukin-8 ELISA kit; IL-8 ELISA kit; C-X-C motif chemokine 8 ELISA kit; Chemokine ELISA kit; C-X-C motif) ligand 8 ELISA kit
縮寫：

CXCL8
Uniprot No.：

P67813
種屬：

Monkey
樣本類型：

serum, plasma, cell culture supernates, tissue homogenates
檢測范圍：

31.25 pg/mL-2000 pg/mL
靈敏度：

7.81 pg/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Immunology
測定原理：

quantitative
測定方法：

Sandwich

精密度：

Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
基因功能參考文獻：
1. Stress decreased IL-8 gene expression in both CeA lesioned and non-lesioned animals. But, CeA lesions increased the tissue expression of IL-8 mRNA prior to and after stress exposure. PMID: 16574374
亞細胞定位：

Secreted.
蛋白家族：

Intercrine alpha (chemokine CxC) family
數據庫鏈接：

KEGG: mcc:613028

STRING: 9544.ENSMMUP00000005115

UniGene: Mmu.3363