Human SPARC-related modular calcium-binding protein 2(SMOC2) ELISA kit

Human SPARC-related modular calcium-binding protein 2(SMOC2) ELISA kit

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中文名稱：

人SPARC相關模塊化鈣結合蛋白2(SMOC2)酶聯免疫試劑盒
貨號：

CSB-EL021843HU
規格：

96T/48T
價格：

￥3600/￥2500
其他：

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產品描述：

人SPARC相關模塊化鈣結合蛋白2(SMOC2)酶聯免疫試劑盒（CSB-EL021843HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織培養上清液、組織勻漿樣本中的SMOC2含量。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL，適用于科學研究中SMOC2的表達水平分析，如探索其在組織再生、疾病模型或細胞功能研究中的作用機制本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

bA270C4A.1 ELISA Kit; bA37D8.1 (secreted modular calcium binding protein 2) ELISA Kit; bA37D8.1 ELISA Kit; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) ELISA Kit; dJ421D16.1 ELISA Kit; MST117 ELISA Kit; MSTP117 ELISA Kit; MSTP140 ELISA Kit; Secreted modular calcium binding protein 2 ELISA Kit; Secreted modular calcium-binding protein 2 ELISA Kit; SMAP 2 ELISA Kit; SMAP-2 ELISA Kit; SMAP2 ELISA Kit; SMOC 2 ELISA Kit; SMOC-2 ELISA Kit; SMOC2 ELISA Kit; SMOC2_HUMAN ELISA Kit; Smooth muscle associated protein 2 ELISA Kit; Smooth muscle-associated protein 2 ELISA Kit; SPARC related modular calcium binding 2 ELISA Kit; SPARC-related modular calcium-binding protein 2 ELISA Kit
縮寫：

SMOC2
Uniprot No.：

Q9H3U7
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, cell culture supernates, tissue homogenates
檢測范圍：

0.156 ng/mL-10 ng/mL
靈敏度：

0.039 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Cardiovascular
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human SMOC2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	97
	Range %	92-103
1:2	Average %	100
	Range %	96-104
1:4	Average %	93
	Range %	87-97
1:8	Average %	99
	Range %	92-103

回收率：

The recovery of human SMOC2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	91	87-95
EDTA plasma (n=4)	94	88-97

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml	OD1	OD2	Average	Corrected
10	2.272	2.211	2.242	2.094
5	1.794	1.765	1.780	1.632
2.5	1.190	1.123	1.157	1.009
1.25	0.787	0.754	0.771	0.623
0.625	0.493	0.482	0.488	0.340
0.312	0.336	0.348	0.342	0.194
0.156	0.236	0.221	0.229	0.081
0	0.149	0.147	0.148

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

功能：

Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.
基因功能參考文獻：
1. SMOC2 was highly expressed in both peritoneal and endometrioma lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue. PMID: 28678915
2. The expression of Smoc2 was significantly higher in hepatocellular carcinoma (HCC) tissues compared with corresponding non-tumor liver tissues. Smoc2 promotes the proliferation of HCC cells through accelerating cell cycle progression. PMID: 28018113
3. L1-mediated CRC progression involves the acquisition of a stem cell-like phenotype, and that SMOC-2 elevation is necessary for L1-mediated induction of more aggressive/invasive CRC properties. PMID: 25915847
4. could not detect an association between SMOC2 gene and AMD. This study tests the candidacy of SMOC2 gene to the etiology of AMD PMID: 22964816
5. SMOC2 SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism. PMID: 23463390
6. mutation in exon 8 of the SMOC2 gene linked to oligodontia PMID: 23317772
7. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects PMID: 22152679
8. The variant rs13208776 in SMOC2 gene does not play a major role in increasing the risk of vitiligo in Jordanian Arab patients. PMID: 20965805
9. SMOC2 is a risk locus for generalized vitiligo and perhaps other autoimmune diseases PMID: 19890347
10. identification of gene, chromosome mapping PMID: 12741954
11. SMOC-2 is a novel angiogenic factor that potentiates angiogenic effects of growth factors PMID: 16774925
12. We tested association between SMOC2 polymorphisms and FEV(1) and FVC. SMOC2 might play an important role in the determination of FEV(1) and FVC PMID: 17204727
13. Although this study specifies rat, the authors studied and discussed the human gene in this study as well. PMID: 12031507
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相關疾病：

Dentin dysplasia 1 (DTDP1)
亞細胞定位：

Secreted, extracellular space, extracellular matrix, basement membrane.
數據庫鏈接：

HGNC: 20323

OMIM: 125400

KEGG: hsa:64094

STRING: 9606.ENSP00000346537

UniGene: Hs.487200

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.